Contrary to common conceptions, bioreactors have more sophisticated analysis and control and with the advent of at-line analyzers more extensive opportunities than chemical reactors. The specialty chemical industry can get a preview of the future from the biopharmaceutical industry.
pH is the most common analytical measurement. pH is important for product purity and environmental compliance. The most stringent pH control requirements occur in bioreactors for biopharmaceuticals where a deviation of 0.05 pH can cause a noticeable degradation in mammalian cell growth rate and product formation rate.