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Integrating quality and process information in a batch context for semi-continuous processes
This paper discusses the scope and approach taken to integrate quality information from various analytical devices through a Laboratory Information Management System (LIMS) with a real-time process information system information connected to a distributed control system (DCS).
By Steve Churchill, Sr. System Specialist, and Mike Williams, Manager, The Dow Chemical Company
The ability to meet and verify achievement of customer specifications is a significant requirement for participation in the high value-added specialty plastics and chemicals businesses. This need is complicated when collecting process information from a semi-continuous manufacturing process. The current ability to monitor, collect and report conformance to customer specification is impeded by the lack of integrated product quality data with process information in a batch or campaign context.
A process information project was chartered to explore and demonstrate a software application which could provide both process and quality information in a batch context. The product being manufactured is a pharmaceutical excipient, which presents additional requirements for traceability and material genealogy.
File Size: 435 KB
File Type: PDF
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